TABLE 1. FAMILY RECRUITMENTa
Column1 Male Female Total
       
Population-based Families*     13235
Case probandsb 4353 4450 8803
Affected relativesb 339 379 718
Unaffected relativesc 7918 10727 18645
Control probandsc 2060 2202 4262
Relatives of controls (Australia only) 178 270 448
Total population-based individuals 14848 18028 32876
       
Clinic-based Families**     1857
Affected probandsb 725 675 1400
Unaffected probandsc 113 270 383
Affected relativesb 446 468 914
Unaffected relativesc 3112 3962 7074
Total clinic-based individuals 4396 5375 9771
       
Total Individuals 19244 23403 42647
Total Families     15092
* Includes population-based case proband families from all sites and population-based control proband families from Australia site.
** Includes all clinic-based proband families (counts family ID of affected and unaffected clinic-based probands).
a. Baseline epi data (excluding proxy completion) for females and males
b. Affected with colorectal cancer at baseline interview or biospecimen collection
c. No history of colon cancer at baseline interview or biospecimen collection
Note: Blood and non-blood relatives/individuals excluding the probands.

 

TABLE 2. FAMILY DATAa
Column1 Column2 Male Female Total
A.Population Based Case Colon Cancer Families      
Probandsb Baseline epi data
4354 4450 8804
  1st Follow-up epi data 2546 2872 5418
  2nd Follow-up epi data 1366 1587 2953
  3rd Follow-up epi data 652 791 1443
  FFQ datae 2096 2409 4505
  Blood/buccal samples 3759 3886 7645
  Polyp material 14 8 22
  Tumor material 3561 3447 7008
  (CRC tumor material)i 3516 3385 6901
  (Other tumor material)j 95 140 235
  Clinical Dx and Treatment info 1563 1526 3089
Relativesc Baseline epi data
7946 10639 18585
  1st Follow-up epi data 5899 8165 14064
  2nd Follow-up epi data 3635 5072 8707
  3rd Follow-up epi data 1075 1478 2553
  FFQ datae 3323 4700 8023
  Blood/buccal samples 4751 6731 11482
  Polyp material 7 8 15
  Tumor material 265 325 590
  (CRC tumor material)i 202 208 410
  (Other tumor material)j 72 131 203
  Clinical Dx and Treatment info 40 44 84
Spouse Controlsf Baseline epi data
178 270 448
  1st Follow-up epi data 159 254 413
  2nd Follow-up epi data 132 224 356
  3rd Follow-up epi data 53 69 122
  FFQ datae 135 197 332
  Blood/buccal samples 149 225 374
  Polyp material 0 0 0
  Tumor material 0 0 0
  (CRC tumor material)i 0 0 0
  (Other tumor material)j 0 0 0
  Clinical Dx and Treatment info 0 0 0
         
B.Population Based Control Colon Cancer Families      
Probandsd Baseline epi data
2060 2202 4262
  1st Follow-up epi data 612 530 1142
  2nd Follow-up epi data 0 1 1
  3rd Follow-up epi data 0 0 0
  FFQ datae 1142 1023 2165
  Blood/buccal samples 1399 1497 2896
  Polyp material 0 0 0
  Tumor material 0 0 0
  (CRC tumor material)i 0 0 0
  (Other tumor material)j 0 0 0
  Clinical Dx and Treatment info 0 0 0
Relativesg Baseline epi data
311 468 779
  1st Follow-up epi data 0 1 1
  2nd Follow-up epi data 0 1 1
  3rd Follow-up epi data 0 0 0
  FFQ datae 260 383 643
  Blood/buccal samples 6 5 11
  Polyp material 0 0 0
  Tumor material 0 0 0
  (CRC tumor material)i 0 0 0
  (Other tumor material)j 0 0 0
  Clinical Dx and Treatment info 0 0 0
         
C.Clinic Based Control Colon Cancer Families*      
Affected Probandsb Baseline epi data
724 675 1399
  1st Follow-up epi data 463 446 909
  2nd Follow-up epi data 250 267 517
  3rd Follow-up epi data 102 124 226
  FFQ datae 247 270 517
  Blood/buccal samples 645 625 1270
  Polyp material 24 29 53
  Tumor material 561 526 1087
  (CRC tumor material)i 540 494 1034
  (Other tumor material)j 74 92 166
  Clinical Dx and Treatment info 239 204 443
Unaffected Probandsd Baseline epi data
113 270 383
  1st Follow-up epi data 99 217 316
  2nd Follow-up epi data 51 96 147
  3rd Follow-up epi data 21 34 55
  FFQ datae 62 164 226
  Blood/buccal samples 101 250 351
  Polyp material 13 27 40
  Tumor material 20 67 87
  (CRC tumor material)i 0 1 1
  (Other tumor material)j 20 67 87
  Clinical Dx and Treatment info 0 0 0
Relativesh Baseline epi data
3557 4429 7986
  1st Follow-up epi data 2736 3500 6236
  2nd Follow-up epi data 1484 2000 3484
  3rd Follow-up epi data 417 582 999
  FFQ datae 1953 2596 4549
  Blood/buccal samples 2983 3814 6797
  Polyp material 120 130 250
  Tumor material 429 542 971
  (CRC tumor material)i 284 318 602
  (Other tumor material)j 156 262 418
  Clinical Dx and Treatment info 14 6 20

a. Baseline epi data (excluding proxy completion) for females and males

b. Affected with colorectal cancer at baseline interview or biospecimen collection

c. Affected and unaffected, blood and non-blood, relatives of population based case probands, at baseline interview.

d. No history of colon cancer at baseline interview.

e. Food Frequency Questionnaire

f. Non blood relation and spouse of case proband recruited to serve as a control.

g. Affected and unaffected, blood and non-blood, relatives of population based control probands, at baseline interview.

h. Affected and unaffected, blood and non-blood, relatives of clinic based probands, at baseline interview or biospecimen collection.

i. Individuals diagnosed with colorectal cancer and at least one colorectal tumor specimen obtained.

j. Individuals diagnosed with non-colorectal cancer and at least one tumor specimen obtained. 

* Includes all clinic-based probands and their blood or non-blood relatives