TABLE 1. FAMILY RECRUITMENTa
 
Column1 Male Female Total
       
Population-based Families*     13188
Case probandsb 4324 4421 8745
Affected relativesb 322 367 689
Unaffected relativesc 7872 10678 18550
Control probandsc 2069 2204 4273
Relatives of controls (Australia only) 178 270 448
Total population-based individuals 14765 17940 32705
       
Clinic-based Families**     1859
Affected probandsb 724 677 1401
Unaffected probandsc 112 270 382
Affected relativesb 444 466 910
Unaffected relativesc 3116 3968 7084
Total clinic-based individuals 4396 5381 9777
       
Total Individuals 19163 23322 42485
Total Families     15047
* Includes population-based case proband families from all sites and population-based control proband families from Australia site.
** Includes all clinic-based proband families (counts family ID of affected and unaffected clinic-based probands).
a. Baseline epi data (excluding proxy completion) for females and males
b. Affected with colorectal cancer at baseline interview or biospecimen collection
c. No history of colon cancer at baseline interview or biospecimen collection
Note: Blood and non-blood relatives/individuals excluding the probands.

 

TABLE 2. FAMILY DATAa
Column1 Column2 Male Female Total
A.Population Based Case Colon Cancer Families      
Probandsb Baseline epi dataa 4324 4421 8745
  1st Follow-up epi data 2593 2926 5519
  2nd Follow-up epi data 1662 1919 3581
  3rd Follow-up epi data 702 908 1610
  FFQ datae 1490 1787 3277
  Blood/buccal samples 3742 3872 7614
  Polyp material 14 8 22
  Tumor material 3502 3398 6900
  (CRC tumor material)i 3437 3334 6771
  (Other tumor material)j 123 149 272
  Clinical Dx and Treatment info 1811 1752 3563
Relativesc Baseline epi dataa 7883 10577 18460
  1st Follow-up epi data 5964 8270 14234
  2nd Follow-up epi data 4098 5804 9902
  3rd Follow-up epi data 1889 2698 4587
  FFQ datae 2844 4092 6936
  Blood/buccal samples 5080 7231 12311
  Polyp material 7 8 15
  Tumor material 285 356 641
  (CRC tumor material)i 215 223 438
  (Other tumor material)j 80 154 234
  Clinical Dx and Treatment info 48 48 96
Spouse Controlsf Baseline epi dataa 178 270 448
  1st Follow-up epi data 159 254 413
  2nd Follow-up epi data 135 225 360
  3rd Follow-up epi data 68 94 162
  FFQ datae 135 197 332
  Blood/buccal samples 149 225 374
  Polyp material 0 0 0
  Tumor material 0 0 0
  (CRC tumor material)i 0 0 0
  (Other tumor material)j 0 0 0
  Clinical Dx and Treatment info 0 0 0
         
B.Population Based Control Colon Cancer Families      
Probandsd Baseline epi dataa 2069 2204 4273
  1st Follow-up epi data 619 533 1152
  2nd Follow-up epi data 56 40 96
  3rd Follow-up epi data 0 0 0
  FFQ datae 1149 1025 2174
  Blood/buccal samples 1401 1497 2898
  Polyp material 0 0 0
  Tumor material 0 0 0
  (CRC tumor material)i 0 0 0
  (Other tumor material)j 0 0 0
  Clinical Dx and Treatment info 0 0 0
Relativesg Baseline epi dataa 311 468 779
  1st Follow-up epi data 1 1 2
  2nd Follow-up epi data 1 1 2
  3rd Follow-up epi data 0 0 0
  FFQ datae 260 383 643
  Blood/buccal samples 5 5 10
  Polyp material 0 0 0
  Tumor material 0 0 0
  (CRC tumor material)i 0 0 0
  (Other tumor material)j 0 0 0
  Clinical Dx and Treatment info 0 0 0
         
C.Clinic Based Colon Cancer Control Families*      
Affected Probandsb Baseline epi dataa 724 677 1401
  1st Follow-up epi data 497 497 994
  2nd Follow-up epi data 294 324 618
  3rd Follow-up epi data 97 122 219
  FFQ datae 221 241 462
  Blood/buccal samples 648 627 1275
  Polyp material 24 29 53
  Tumor material 576 535 1111
  (CRC tumor material)i 557 500 1057
  (Other tumor material)j 87 107 194
  Clinical Dx and Treatment info 252 211 463
Unaffected Probandsd Baseline epi dataa 112 270 382
  1st Follow-up epi data 102 236 338
  2nd Follow-up epi data 63 136 199
  3rd Follow-up epi data 20 39 59
  FFQ datae 51 150 201
  Blood/buccal samples 101 252 353
  Polyp material 13 27 40
  Tumor material 18 68 86
  (CRC tumor material)i 0 3 3
  (Other tumor material)j 18 67 85
  Clinical Dx and Treatment info 0 0 0
Relativesh Baseline epi dataa 3560 4434 7994
  1st Follow-up epi data 2907 3700 6607
  2nd Follow-up epi data 1783 2352 4135
  3rd Follow-up epi data 593 863 1456
  FFQ datae 1803 2412 4215
  Blood/buccal samples 3077 3958 7035
  Polyp material 120 130 250
  Tumor material 437 552 989
  (CRC tumor material)i 289 324 613
  (Other tumor material)j 162 270 432
  Clinical Dx and Treatment info 14 8 22

a. Baseline epi data (excluding proxy completion) for females and males

b. Affected with colorectal cancer at baseline interview or biospecimen collection

c. Affected and unaffected, blood and non-blood, relatives of population based case probands, at baseline interview.

d. No history of colon cancer at baseline interview.

e. Food Frequency Questionnaire

f. Non blood relation and spouse of case proband recruited to serve as a control.

g. Affected and unaffected, blood and non-blood, relatives of population based control probands, at baseline interview.

h. Affected and unaffected, blood and non-blood, relatives of clinic based probands, at baseline interview or biospecimen collection.

i. Individuals diagnosed with colorectal cancer and at least one colorectal tumor specimen obtained.

j. Individuals diagnosed with non-colorectal cancer and at least one tumor specimen obtained. 

* Includes all clinic-based probands and their blood or non-blood relatives