Clinical Diagnosis and Treatment

Module: colorectal-path

Module Contents

  1. colon-clinical-treatment


1CENTER_NOnumber (2,0)Required:true
Center identification number.
Allowable Values
11Sinai Health Systems (formerly Cancer Care Ontario)
12Cedars-Sinai & Cleveland Clinic (formerly USC Consortium)
13University of Melbourne
14University of Hawaii Cancer Center
15Mayo Clinic
16Fred Hutch, Seattle
17UCSF: University of California at San Francisco (formerly CPIC, originally Northern California (NCCC))


2PERSON_IDstring (12)Required:true
Number that uniquely identifies an individual.

3CRC1_TUMOR_NOnumber (2,0)Required:true
PERSON_NO, TUMOR_NO uniquely identifies each tumor in the Informatics Centre. Tumor number should correspond with information from the CANCER file

4CRC1_ICDstring (7)Required:false
ICD CODE: ICD0 code
5CRC1_DXDATEstring (8)Required:false
Diagnosis Date Of First CRC Primary(s) in the Eligibility Period:
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



6CRC1_SURGnumber (1,0)Required:false
Surgical treatment performed
Allowable Values
1Yes
2No
8Not Asked
9Unknown


7CRC1_SURG_TYPEnumber (2,0)Required:false
Type of surgical treatment (Can use SEER coding to derive)
Allowable Values
2Local tumor destruction, i.e. laser, electrocautery
3Local surgical excision with specimen i.e. trans anal excision, polypectomy, snare
4Right Hemi colectomy
5Left Hemi colectomy
6Hemi colectomy side not specified: not total
7Low Anterior resection
8Total Colectomy
9Total Proctectomy
10Total Proctocolectomy
11Abdominoperineal resection
12Segmental / Wedge / Partial Resection NOS
13Sigmoidectomy / Sigmoid Colectomy
77Other Surgery


8CRC1_SURG_TYPE_TXTstring (250)Required:false
Free text describing other surgery
9CRC1_SURG_DATEstring (8)Required:false
Date of 1st resection:
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



10CRC1_SURG_LOCALnumber (1,0)Required:false
Operative findings indicating completeness of excision: (obtain information from the operative report and/or the discharge summary NOT pathology report)
Allowable Values
1Tumor not entirely resected
2Tumor entirely resected
8Not asked.
9Unknown


11CRC1_SURG_OTHORGnumber (1,0)Required:false
Were other organs (partial or total) removed at definitive surgery?
Allowable Values
1Yes and site/organ specified
2Yes but site/organ not specified
3No
8Not asked
9Unknown


12CRC1_SURG_OTHORG_SM_INTESTnumber (1,0)Required:false
If small intestine (partial or total) were removed, please specify:
Allowable Values
1yes
2not reported


13CRC1_SURG_OTHORG_LIVERnumber (1,0)Required:false
If liver (partial or total) was removed, please specify:
Allowable Values
1yes
2not reported


14CRC1_SURG_OTHORG_APPENDIXnumber (1,0)Required:false
If appendix (partial or total) was removed, please specify:
Allowable Values
1yes
2not reported


15CRC1_SURG_OTHORG_OVARY_NOSnumber (1,0)Required:false
If ovary (partial or total) were removed and no information on which side (left or right) , please specify:
Allowable Values
1yes
2not reported


16CRC1_SURG_OTHORG_OVARY_Rnumber (1,0)Required:false
If right ovary (partial or total) was removed, please specify:
Allowable Values
1yes
2not reported


17CRC1_SURG_OTHORG_OVARY_Lnumber (1,0)Required:false
If left ovary (partial or total) was removed, please specify:
Allowable Values
1yes
2not reported


18CRC1_SURG_OTHORG_OVARY_Bnumber (1,0)Required:false
If both ovaries (partial or total) were removed, please specify:
Allowable Values
1yes
2not reported


19CRC1_SURG_OTHORG_SPLEENnumber (1,0)Required:false
If spleen (partial or total) was removed, please specify:
Allowable Values
1yes
2not reported


20CRC1_SURG_OTHORG_BLADDERnumber (1,0)Required:false
If bladder (partial or total) was removed, please specify:
Allowable Values
1yes
2not reported


21CRC1_SURG_OTHORG_OTHnumber (1,0)Required:false
If other organs (partial or total) were removed, please specify:
Allowable Values
1yes
2not reported


22CRC1_SURG_OTHORG_OTH_TXTstring (250)Required:false
Free text describing other organs (partial or total) that were removed if more than one separate with commas

23CRC1_SURG_MARGINnumber (1,0)Required:false
Did the tumor reach surgical resection margins? (Source: Pathology report)
Allowable Values
1Positive, proximal (Tumor is seen at proximal surgical resection margin)
2Positive, distal (Tumor is seen at distal surgical resection margin)
3Positive, radial (Tumor is seen at radial surgical resection margin)
4Positive, more than one margins defined.
5Positive, NOS (Tumor is seen at surgical resection margin, margin not defined)
6Negative (all surgical resection margins are free of tumor)
8Not Asked
9Unknown


24CRC1_METnumber (1,0)Required:false
Metastatic Disease Found at the time of surgery (from perative report)
Allowable Values
1Yes and site/organ specified
2Yes but site/organ not specified
3No
8Not asked
9Unknown


25CRC1_MET_ASCITESnumber (1,0)Required:false
Site of Metastatic Disease: ASCITES
Allowable Values
1yes
2not reported


26CRC1_MET_MESEN_LNnumber (1,0)Required:false
Site of Metastatic Disease: Mesenteric lymph nodes, other than in mesentery of planned resection
Allowable Values
1yes
2not reported


27CRC1_MET_LIVERnumber (1,0)Required:false
Site of Metastatic Disease: Liver
Allowable Values
1yes
2not reported


28CRC1_MET_LUNGnumber (1,0)Required:false
Site of Metastatic Disease: Lung
Allowable Values
1yes
2not reported


29CRC1_MET_OMENTUMnumber (1,0)Required:false
Site of Metastatic Disease: Omentum
Allowable Values
1yes
2not reported


30CRC1_MET_ABD_WALLnumber (1,0)Required:false
Site of Metastatic Disease: Abdominal wall
Allowable Values
1yes
2not reported


31CRC1_MET_OVARYnumber (1,0)Required:false
Site of Metastatic Disease: Ovary(s)
Allowable Values
1yes
2not reported


32CRC1_MET_BONEnumber (1,0)Required:false
Site of Metastatic Disease: Bone
Allowable Values
1yes
2not reported


33CRC1_MET_PERITOnumber (1,0)Required:false
Site of Metastatic Disease: Peritoneum
Allowable Values
1yes
2not reported


34CRC1_MET_MESENnumber (1,0)Required:false
Site of Metastatic Disease: Mesentery
Allowable Values
1yes
2not reported


35CRC1_MET_OTHnumber (1,0)Required:false
Site of Metastatic Disease: Other
Allowable Values
1yes
2not reported


36CRC1_MET_OTH_TXTstring (250)Required:false
Free text describing other site of Metastatic Disease. If more than one separate with commas.

37CRC1_MET_RESECTnumber (1,0)Required:false
Was this metastasis resected immediately (within 3 months) after baseline surgery)
Allowable Values
1All metastases entirely resected
2At least one metastasis not entirely resected
3Not resected (No surgery)
8Not Asked
9Unknown

38CRC1_MET_RESECT_DATEstring (8)Required:false
Date metastasis was resected (only if metastasis was completely or incompletely resected) Month of metastasis resection: Day of metastasis resection: Year of metastasis resection:
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



39CRC1_Tnumber (1,0)Required:false
Tumor Stage at Baseline (0-4)
Allowable Values
0Carcinoma in situ/TIS
1Tumor invades submucosa
2Tumor invades muscularis propria
3Tumor invades through muscularis propria into submucosa or into non peritonealized pericolic or perirectal tissues
4Tumor directly invades other organs/structures/perforates visceral peritonium
8Not Asked
9Unknown


40CRC1_Nnumber (1,0)Required:false
Nodal stage at Baseline (0-3)
Allowable Values
0No regional lymph node metastasis
1Metastasis in 1 to 3 regional lymph nodes
2Metastasis in 4 or more regional lymph nodes
8Not Asked
9Unknown


41CRC1_Mnumber (1,0)Required:false
Metastasis stage at Baseline (0-1)
Allowable Values
0No distant metastasis
1Distant metastasis is present
8Not Asked
9Unknown


42CRC1_T_SRCnumber (1,0)Required:false
Source of information for tumor stage:
Allowable Values
1Pathology Report
2Clinic Note/Discharge Summary
3Other (Specify):
8Not Asked
9Unknown


43CRC1_T_SRC_TXTstring (250)Required:false
Source of information for tumor stage: OTHER

44CRC1_N_SRCnumber (1,0)Required:false
Source of information for nodal stage:
Allowable Values
1Pathology Report
2Clinic Note/Discharge Summary
3Other (Specify):
8Not Asked
9Unknown


45CRC1_N_SRC_TXTstring (250)Required:false
Source of information for nodal stage: OTHER

46CRC1_M_SRCnumber (1,0)Required:false
Source of information for metastasis stage):
Allowable Values
1Pathology Report
2Clinic Note/Discharge Summary
3Operative Note
4Radiology report (US, CT, MRI etc.)
5Other (Specify):
8Not Asked
9Unknown


47CRC1_M_SRC_TXTstring (250)Required:false
Source of information for metastasis stage):-OTHER

48CRC1_CHEMOnumber (1,0)Required:false
Was chemotherapy given for treatment of the primary colorectal cancer(s)?
Allowable Values
1Yes
2No
8Not Asked
9Unknown


49CRC1_CHEMO_METHODnumber (1,0)Required:false
What method of chemotherapy was applied for treatment of the primary colorectal cancer(s)? Note: Multiple methods and agents are possible. If so they should be recorded in order given ie Neo Adjuvant first > Adjuvant > Palliative last
Allowable Values
1Adjuvant
2Palliative
3Pseudo Adjuvant
4Neo Adjuvant (pre operative)
8Not Asked
9Unknown

50CRC1_CHEMO1_DATEstring (8)Required:false
Date of 1st chemotherapy treatment of the CRC primary(s) in the eligibility period
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



51CRC1_CHEMO1_AGTnumber (1,0)Required:false
Pseudo gateway question to capture overall “missing/unknown agent”
Allowable Values
1specified
8missing
9unknown


52CRC1_CHEMO1_AGT_5FUnumber (1,0)Required:false
5 FU / FLUOROURACIL/ ADRUCIL CHEMOTHERAPEUTIC AGENT FOR BASELINE DIAGNOSIS first course only. Does not include medications given to control or suppress side effect. Also the list is abbreviated and another variable “other” added to list additional drugs
Allowable Values
1yes
2not reported


53CRC1_CHEMO1_AGT_FAnumber (1,0)Required:false
FA (FOLINIC ACID) / LEUCOVORIN / WELLCOVORIN CHEMOTHERAPEUTIC AGENT FOR BASELINE DIAGNOSIS
Allowable Values
1yes
2not reported


54CRC1_CHEMO1_AGT_CPT11number (1,0)Required:false
CPT11/ IRINOTECAN / CAMPTOSAR CHEMOTHERAPEUTIC AGENT FOR BASELINE DIAGNOSIS
Allowable Values
1yes
2not reported


55CRC1_CHEMO1_AGT_OXALnumber (1,0)Required:false
OXALIPLATIN / ELOXATIN CHEMOTHERAPEUTIC AGENT FOR BASELINE DIAGNOSIS
Allowable Values
1yes
2not reported


56CRC1_CHEMO1_AGT_LEVAnumber (1,0)Required:false
LEVAMISOLE CHEMOTHERAPEUTIC AGENT FOR BASELINE DIAGNOSIS
Allowable Values
1yes
2not reported


57CRC1_CHEMO1_AGT_XELOnumber (1,0)Required:false
XELODA / CAPECITABINE CHEMOTHERAPEUTIC AGENT FOR BASELINE DIAGNOSIS
Allowable Values
1yes
2not reported


58CRC1_CHEMO1_AGT_AVASnumber (1,0)Required:false
AVASTIN / BEVACIZUMAB CHEMOTHERAPEUTIC AGENT FOR BASELINE DIAGNOSIS
Allowable Values
1yes
2not reported


59CRC1_CHEMO1_AGT_ERBInumber (1,0)Required:false
ERBITUX/ CETUXIMAB CHEMOTHERAPEUTIC AGENT FOR BASELINE DIAGNOSIS
Allowable Values
1yes
2not reported


60CRC1_CHEMO1_AGT_GEMZnumber (1,0)Required:false
GEMZAR CHEMOTHERAPEUTIC AGENT FOR BASELINE DIAGNOSIS
Allowable Values
1yes
2not reported


61CRC1_CHEMO1_AGT_OTHnumber (1,0)Required:false
OTHER AGENT CHEMOTHERAPEUTIC AGENT FOR BASELINE DIAGNOSIS
Allowable Values
1yes
2not reported


62CRC1_CHEMO1_AGT_OTH_TXTstring (250)Required:false
NAME of OTHER AGENT, If more than one separate with commas.

63CRC1_RADnumber (1,0)Required:false
Was radiation given for treatment of the primary colorectal cancer(s)?
Allowable Values
1Yes
2No
8Not Asked
9Unknown


64CRC1_RAD_METHODnumber (1,0)Required:false
What method of radiotherapy was applied for treatment of the primary colorectal cancer(s)?
Allowable Values
1Adjuvant
2Palliative
3Pseudo Adjuvant
4Neo Adjuvant (pre operative)
8Not Asked
9Unknown

65CRC1_RAD1_DATEstring (8)Required:false
Date of 1st radiotherapy treatment of the CRC primary(s) in the eligibility period
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



66CRC1_TREAT_OTHnumber (1,0)Required:false
Were other treatment methods applied for primary colorectal cancer(s)?
Allowable Values
1Yes only one other treatment
2Yes only 2 other treatments
3No
8Not Asked
9Unknown


67CRC1_TREAT_OTH_TXTstring (250)Required:false
Free text describing 1st other treatment. If more than one separate with commas.

68CRC1_SYNCnumber (1,0)Required:false
Were synchronous CRC primaries diagnosed at baseline?
Allowable Values
1Yes
2No


69CRC1_SYNC_NUMnumber (2,0)Required:false
#_____ of SYNCHRONOUS PRIMARY(S)
Allowable Values
1 to 8 or 88, 99Range
88Not asked
99unknown


70CRC1_SYNC2_TUMOR_NOnumber (2,0)Required:true
Tumor number should correspond with information from the CANCER file

71CRC1_SYNC2_ICDstring (7)Required:false
ICD CODE of 2nd largest SYNCHRONOUS CRC PRIMARY (PRIMARY_2) :
72CRC1_SYNC2_DXDATEstring (8)Required:false
DIAGNOSIS DATE OF 2nd SYNCHRONOUS CRC PRIMARY IN THE ELIGIBILITY PERIOD
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



73CRC1_SYNC2_SURG_TYPEnumber (2,0)Required:false
Surgical treatment for 2nd synchronous primary CRC (Can use SEER coding to derive)
Allowable Values
1No Surgery
2Local tumor destruction, i.e. laser, electrocautery
3Local surgical excision with specimen i.e. trans anal excision, polypectomy, snare
4Right Hemi colectomy
5Left Hemi colectomy
6Hemi colectomy Side not specified: not total
7Low Anterior resection
8Total Colectomy
9Total Proctectomy
10Total Proctocolectomy
11Abdominoperineal resection
12Segmental / Wedge / Partial Resection NOS
77Other (Specify):
88Not Asked
99Unknown


74CRC1_SYNC2_SURG_TYPE_TXTstring (250)Required:false
Surgical treatment for 2nd synchronous primary CRC (Can use SEER coding to derive) OTHER

75CRC1_SYNC2_SURG_LOCALnumber (1,0)Required:false
Operative findings , local (residual tumor) for 2nd synchronous primary CRC (obtain information from the operative report and/or the discharge summary NOT pathology report)
Allowable Values
1Tumor not entirely resected
2Tumor entirely resected
8Not Asked
9Unknown


76CRC1_SYNC2_SURG_MARGINnumber (1,0)Required:false
Did the 2nd synchronous primary CRC reach surgical resection margins? (Source: Pathology report)
Allowable Values
1Positive, proximal (Tumor is seen at proximal surgical resection margin)
2Positive, distal (Tumor is seen at distal surgical resection margin)
3Positive, radial (Tumor is seen at radial surgical resection margin)
4Positive, more than one margins defined.
5Positive, NOS (Tumor is seen at surgical resection margin, margin not defined)
6Negative (all surgical resection margins are free of tumor)
8Not Asked
9Unknown


77CRC1_SYNC3_TUMOR_NOnumber (2,0)Required:true
Tumor number should correspond with information from the CANCER file

78CRC1_SYNC3_ICDstring (7)Required:false
ICD code for 3rd largest SYNCHRONOUS CRC PRIMARY (PRIMARY_3)
79CRC1_SYNC3_DXDATEstring (8)Required:false
DIAGNOSIS DATE OF 3rd SYNCHRONOUS CRC PRIMARY IN THE ELIGIBILITY PERIOD
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



80CRC1_SYNC3_SURG_TYPEnumber (2,0)Required:false
Surgical treatment for 3rd synchronous primary CRC (Can use SEER coding to derive)
Allowable Values
01No Surgery (go to section 3)
02Local tumor destruction, i.e. laser, electrocautery
03Local surgical excision with specimen i.e. trans anal excision, polypectomy, snare
04Right Hemi colectomy
05Left Hemi colectomy
06Hemi colectomy Side not specified: not total
07Low Anterior resection
08Total Colectomy
09Total Proctectomy
10Total Proctocolectomy
11Abdominoperineal resection
12Segmental / Wedge / Partial Resection NOS
77Other (Specify):
88Not Asked
99Unknown


81CRC1_SYNC3_SURG_TYPE_TXTstring (250)Required:false
Surgical treatment for 3rd synchronous primary CRC (Can use SEER coding to derive) OTHER

82CRC1_SYNC3_SURG_LOCALnumber (1,0)Required:false
Operative findings , local (residual tumor) for 3rd synchronous primary CRC (obtain information from the operative report and/or the discharge summary NOT pathology report)
Allowable Values
1Tumor not entirely resected
2Tumor entirely resected
8Not Asked
9Unknown


83CRC1_SYNC3_SURG_MARGINnumber (1,0)Required:false
Did the 3rd synchronous primary CRC reach surgical resection margins? (Source: Pathology report)
Allowable Values
1Positive, proximal (Tumor is seen at proximal surgical resection margin)
2Positive, distal (Tumor is seen at distal surgical resection margin)
3Positive, radial (Tumor is seen at radial surgical resection margin)
4Positive, more than one margins defined.
5Positive, NOS (Tumor is seen at surgical resection margin, margin not defined)
6Negative (all surgical resection margins are free of tumor)
8Not Asked
9Unknown


84LR_RECURnumber (1,0)Required:true
Did the patient have at least one locoregional recurrence after CRC diagnosis? (Ideally interval between diagnosis date and final chart review date should be at least 4 years)
Allowable Values
1Yes and site/organ specified
2Yes but site/organ not specified
3No
8Not asked
9Unknown

85LR1_DATEstring (8)Required:false
Date of 1st locoregional recurrence
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



86LR1_ANASTnumber (1,0)Required:false
Site(s) of involvement at time of first locoregional recurrence (please circle all that apply): Anastomosis:
Allowable Values
1yes
2not reported


87LR1_MESENnumber (1,0)Required:false
Site(s) of involvement at time of first locoregional recurrence (please circle all that apply): Mesentery
Allowable Values
1yes
2not reported


88LR1_ABD_WALLnumber (1,0)Required:false
Site(s) of involvement at time of first locoregional recurrence (please circle all that apply): Abdominal Wall (not incisional)
Allowable Values
1yes
2not reported


89LR1_INCSnumber (1,0)Required:false
Site(s) of involvement at time of first locoregional recurrence (please circle all that apply): Incisional
Allowable Values
1yes
2not reported


90LR1_PELVISnumber (1,0)Required:false
Site(s) of involvement at time of first locoregional recurrence (please circle all that apply): Pelvis
Allowable Values
1yes
2not reported


91LR1_OTHnumber (1,0)Required:false
Site(s) of involvement at time of first locoregional recurrence (please circle all that apply): OTHER
Allowable Values
1yes
2not reported


92LR1_OTH_TXTstring (250)Required:false
LocoRegional Recurrence 1st other site Comma separated list of other site(s)

93LR1_TREATnumber (1,0)Required:false
Did patient receive treatment for locoregional recurrence?
Allowable Values
1Yes
2No
8Not Asked
9Unknown


94LR1_SURGnumber (1,0)Required:false
Surgical treatment given for locoregional recurrence?
Allowable Values
1Yes
2No
8Not Asked
9Unknown


95LR1_SURG_LOCALnumber (1,0)Required:false
Surgery for locoregional recurrence:
Allowable Values
1Recurrent tumor entirely resected
2Recurrent tumor not entirely resected
8Not Asked
9Unknown


96LR1_SURG_TXTstring (250)Required:false
If Surgery for locoregional recurrence: 1 or 2, then specify (describe procedure ?text format)

97LR1_CHEMOnumber (1,0)Required:false
Was chemotherapy given for locoregional recurrence?
Allowable Values
1Yes
2No
8Not Asked
9Unknown


98LR1_CHEMO_METHODnumber (1,0)Required:false
What method of chemotherapy was applied for treatment of the locoregional recurrence(s) Note: Multiple methods and agents are possible. If so they should be recorded in order given ie Neo Adjuvant first > Adjuvant > Palliative last
Allowable Values
1Adjuvant
2Palliative
3Pseudo Adjuvant
4Neo Adjuvant (pre operative)
8Not Asked
9Unknown

99LR1_CHEMO1_DATEstring (8)Required:false
Date of 1st chemotherapy treatment of the locoregional recurrence.
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



100LR1_CHEMO1_AGTnumber (1,0)Required:false
Pseudo gateway question to capture overall “missing/unknown agent”
Allowable Values
1specified
8Not Asked
9Unknown


101LR1_CHEMO1_AGT_5FUnumber (1,0)Required:false
5 FU / FLUOROURACIL/ ADRUCIL CHEMOTHERAPEUTIC AGENT first course only. Does not include medications given to control or suppress side effect. Also the list is abbreviated and another variable “other” added to list additional drugs
Allowable Values
1yes
2not reported


102LR1_CHEMO1_AGT_FAnumber (1,0)Required:false
FA (FOLINIC ACID) / LEUCOVORIN / WELLCOVORIN
Allowable Values
1yes
2not reported


103LR1_CHEMO1_AGT_CPT11number (1,0)Required:false
CPT11/ IRINOTECAN / CAMPTOSAR
Allowable Values
1yes
2not reported


104LR1_CHEMO1_AGT_OXALnumber (1,0)Required:false
OXALIPLATIN / ELOXATIN
Allowable Values
1yes
2not reported


105LR1_CHEMO1_AGT_LEVAnumber (1,0)Required:false
LEVAMISOLE
Allowable Values
1yes
2not reported


106LR1_CHEMO1_AGT_XELOnumber (1,0)Required:false
XELODA / CAPECITABINE
Allowable Values
1yes
2not reported


107LR1_CHEMO1_AGT_AVASnumber (1,0)Required:false
AVASTIN / BEVACIZUMAB
Allowable Values
1yes
2not reported


108LR1_CHEMO1_AGT_ERBInumber (1,0)Required:false
ERBITUX/ CETUXIMAB
Allowable Values
1yes
2not reported


109LR1_CHEMO1_AGT_GEMZnumber (1,0)Required:false
GEMZAR
Allowable Values
1yes
2not reported


110LR1_CHEMO1_AGT_OTHnumber (1,0)Required:false
OTHER AGENT CHEMOTHERAPEUTIC AGENT
Allowable Values
1yes
2not reported


111LR1_CHEMO1_AGT_OTH_TXTstring (250)Required:false
Free text describing OTHER CHEMOTHERAPEUTIC AGENT for first locoregional recurrence diagnosis. If more than one separate with commas.

112LR1_RADnumber (1,0)Required:false
Was radiotherapy given for locoregional recurrence?
Allowable Values
1Yes
2No
8Not Asked
9Unknown


113LR1_RAD_METHODnumber (1,0)Required:false
What method of radiotherapy was applied for treatment of the locoregional recurrence?
Allowable Values
1Adjuvant
2Palliative
3Pseudo Adjuvant
4Neo Adjuvant (pre operative)
8Not Asked
9Unknown

114LR1_RAD1_DATEstring (8)Required:false
Date of 1st radiotherapy treatment of the locoregional recurrence.
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



115LR1_TREAT_OTHnumber (1,0)Required:false
Were other treatment methods applied for first locoregional recurrence?
Allowable Values
1Yes 1 other treatment
2Yes 2 other treatments
3No
8Not Asked
9Unknown


116LR1_TREAT_OTH_TXTstring (250)Required:false
Free text describing first other treatment methods applied for first locoregional recurrence. Comma separated list of other agents(s

117LR_ADDnumber (1,0)Required:false
Pseudo entry question to section on additional LR sites, ie should be yes if any LR_ADD below are yes.
Allowable Values
1Yes and site/organ specified
2Yes but site/organ not specified
3No
8Not asked
9Unknown


118LR_ADD_ANASTnumber (1,0)Required:false
Locoregional recurrence site(s) after the 1st site(s) identified Anastomosis:
Allowable Values
1yes
2not reported

119LR_ADD_ANAST_DATEstring (8)Required:false
Diagnosed Month Diagnosed Day (optional) Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



120LR_ADD_MESENnumber (1,0)Required:false
Locoregional recurrence site(s) after the 1st site(s) identified Mesentery
Allowable Values
1yes
2not reported

121LR_ADD_MESEN_DATEstring (8)Required:false
Diagnosed Month Diagnosed Day (optional) Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



122LR_ADD_ABD_WALLnumber (1,0)Required:false
Locoregional recurrence site(s) after the 1st site(s) identified Abdominal Wall (not incisional)
Allowable Values
1yes
2not reported

123LR_ADD_ABD_WALL_DATEstring (8)Required:false
Diagnosed Month Diagnosed Day (optional) Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



124LR_ADD_INCSnumber (1,0)Required:false
Locoregional recurrence site(s) after the 1st site(s) identified Incisional
Allowable Values
1yes
2not reported

125LR_ADD_INCS_DATEstring (8)Required:false
Diagnosed Month Diagnosed Day (optional) Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



126LR_ADD_PELVISnumber (1,0)Required:false
Locoregional recurrence site(s) after the 1st site(s) identified Pelvis
Allowable Values
1yes
2not reported

127LR_ADD_PELVIS_DATEstring (8)Required:false
Diagnosed Month Diagnosed Day (optional) Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



128LR_ADD_OTHnumber (1,0)Required:false
Locoregional recurrence site(s) after the 1st site(s) identified Other
Allowable Values
1yes
2not reported


129LR_ADD_OTH_TXTstring (250)Required:false
Free text describing additional LR site
130LR_ADD_OTH_DATEstring (8)Required:false
Diagnosed Month Diagnosed Day (optional) Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



131DST_Rnumber (1,0)Required:true
Did the patient have a distant recurrence after CRC diagnosis (after start date to final chart date available)?
Allowable Values
1Yes and site/organ specified
2Yes but site/organ not specified
3No
8Not asked
9Unknown

132DST_R1_DATEstring (8)Required:false
Date of first distant recurrence
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



133DST_R1_LIVERnumber (1,0)Required:false
Site(s) of involvement at time of first distant recurrence Liver
Allowable Values
1yes
2not reported


134DST_R1_LUNGnumber (1,0)Required:false
Site(s) of involvement at time of first distant recurrence Lung
Allowable Values
1yes
2not reported


135DST_R1_BONEnumber (1,0)Required:false
Site(s) of involvement at time of first distant recurrence Bone
Allowable Values
1yes
2not reported


136DST_R1_ASCITESnumber (1,0)Required:false
Site(s) of involvement at time of first distant recurrence Ascites
Allowable Values
1yes
2not reported


137DST_R1_NONMES_LNnumber (1,0)Required:false
Site(s) of involvement at time of first distant recurrence Non mesenteric lymph nodes (except supraclavicular)
Allowable Values
1yes
2not reported


138DST_R1_NONMES_LN_TXTstring (250)Required:false
Free text describing specific non mesenteric lymph nodes (except supraclavicular)

139DST_R1_SUPRA_LNnumber (1,0)Required:false
Site(s) of involvement at time of first distant recurrence Supraclavicular nodes
Allowable Values
1yes
2not reported


140DST_R1_BRAINnumber (1,0)Required:false
Site(s) of involvement at time of first distant recurrence Brain
Allowable Values
1yes
2not reported


141DST_R1_SKINnumber (1,0)Required:false
Site(s) of involvement at time of first distant recurrence: Skin, except incision Specify site (text):
Allowable Values
1yes
2not reported


142DST_R1_SKIN_TXTstring (250)Required:false
Free text describing specific skin site of first distant recurrence
Allowable Values
1yes
2not reported


143DST_R1_ADRENALnumber (1,0)Required:false
Site(s) of involvement at time of first distant recurrence: Adrenal gland
Allowable Values
1yes
2not reported


144DST_R1_OTHnumber (1,0)Required:false
Site(s) of involvement at time of first distant recurrence Other Specify site (text):
Allowable Values
1yes
2not reported


145DST_R1_OTH_TXTstring (250)Required:false
Free text describing other site of first distant recurrence

146DST_R1_TREATnumber (1,0)Required:false
Did the patient undergo treatment for distant recurrence?:
Allowable Values
1Yes
2No
8Not Asked
9Unknown


147DST_R1_SURGnumber (1,0)Required:false
Did patient undergo surgical treatment for distant recurrence?
Allowable Values
1Yes
2No
8Not Asked
9Unknown


148DST_R1_SURG_LOCALnumber (1,0)Required:false
Surgery for distant recurrence
Allowable Values
1Recurrent tumor entirely resected
2Recurrent tumor not entirely resected
8Not Asked
9Unknown


149DST_R1_SURG_TXTstring (250)Required:false
Free text describing other surgery for distant recurrence 1 or 2

150DST_R1_CHEMOnumber (1,0)Required:false
Did patient undergo chemotherapy for distant recurrence?
Allowable Values
1Yes
2No
8Not Asked
9Unknown


151DST_R1_CHEMO_METHODnumber (1,0)Required:false
If chemotherapy was given, what method of chemotherapy was applied for treatment of the distant recurrence? Note: Multiple methods and agents are possible. If so they should be recorded in order given ie Neo Adjuvant first > Adjuvant > Palliative last
Allowable Values
1Adjuvant
2Palliative
3Pseudo Adjuvant
4Neo adjuvant (pre operative)
8Not Asked
9Unknown

152DST_R1_CHEMO1_DATEstring (8)Required:false
Date of 1st chemotherapy treatment of the distant recurrence.
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



153DST_R1_CHEMO1_AGTnumber (1,0)Required:false
Pseudo gateway question to capture overall “missing/unknown agent
Allowable Values
1specified
8Not Asked
9Unknown


154DST_R1_CHEMO1_AGT_5FUnumber (1,0)Required:false
5 FU / FLUOROURACIL/ ADRUCIL CHEMOTHERAPEUTIC AGENT first course only. Does not include medications given to control or suppress side effect. Also the list is abbreviated and another variable “other” added to list additional drugs
Allowable Values
1yes
2not reported


155DST_R1_CHEMO1_AGT_FAnumber (1,0)Required:false
FA (FOLINIC ACID) / LEUCOVORIN / WELLCOVORIN
Allowable Values
1yes
2not reported


156DST_R1_CHEMO1_AGT_CPT11number (1,0)Required:false
CPT11/ IRINOTECAN / CAMPTOSAR
Allowable Values
1yes
2not reported


157DST_R1_CHEMO1_AGT_OXALnumber (1,0)Required:false
OXALIPLATIN / ELOXATIN
Allowable Values
1yes
2not reported


158DST_R1_CHEMO1_AGT_LEVAnumber (1,0)Required:false
LEVAMISOLE
Allowable Values
1yes
2not reported


159DST_R1_CHEMO1_AGT_XELOnumber (1,0)Required:false
XELODA / CAPECITABINE
Allowable Values
1yes
2not reported


160DST_R1_CHEMO1_AGT_AVASnumber (1,0)Required:false
AVASTIN / BEVACIZUMAB
Allowable Values
1yes
2not reported


161DST_R1_CHEMO1_AGT_ERBInumber (1,0)Required:false
ERBITUX/ CETUXIMAB
Allowable Values
1yes
2not reported


162DST_R1_CHEMO1_AGT_GEMZnumber (1,0)Required:false
GEMZAR
Allowable Values
1yes
2not reported


163DST_R1_CHEMO1_AGT_OTHnumber (1,0)Required:false
OTHER AGENT CHEMOTHERAPEUTIC AGENT
Allowable Values
1yes
2not reported


164DST_R1_CHEMO1_AGT_OTH_TXTstring (250)Required:false
Free text describing OTHER CHEMOTHERAPEUTIC AGENT for distant recurrence diagnosis. If more than one separate with commas.

165DST_R1_RADnumber (1,0)Required:false
Was radiotherapy treatment given for distant recurrence?
Allowable Values
1Yes
2No
8Not Asked
9Unknown


166DST_R1_RAD_METHODnumber (1,0)Required:false
What method of radiotherapy was applied for treatment of the 1st distant recurrence?
Allowable Values
1Adjuvant
2Palliative
3Pseudo Adjuvant
4Neo Adjuvant (pre operative)
8Not Asked
9Unknown

167DST_R1_RAD1_DATEstring (8)Required:false
Date of 1st radiotherapy treatment of the distant recurrence.
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



168DST_R_ADDnumber (1,0)Required:false
pseudo gateway for additional distant recurrence site(s)
Allowable Values
1Yes and site/organ specified
2Yes but site/organ not specified
3No
8Not asked
9Unknown


169DST_R_ADD_LIVERnumber (1,0)Required:false
Site(s) of involvement at time of additional distant recurrence Liver
Allowable Values
1yes
2not reported

170DST_R_ADD_LIVER_DATEstring (8)Required:false
Additional Distant Recurrence First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



171DST_R_ADD_LUNGnumber (1,0)Required:false
Site(s) of involvement at time of additional distant recurrence Lung
Allowable Values
1yes
2not reported

172DST_R_ADD_LUNG_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



173DST_R_ADD_BONEnumber (1,0)Required:false
Site(s) of involvement at time of additional distant recurrence Bone
Allowable Values
1yes
2not reported

174DST_R_ADD_BONE_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



175DST_R_ADD_ASCITESnumber (1,0)Required:false
Site(s) of involvement at time of additional distant recurrence Ascites
Allowable Values
1yes
2not reported

176DST_R_ADD_ASCITES_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



177DST_R_ADD_NONMES_LNnumber (1,0)Required:false
Site(s) of involvement at time of additional distant recurrence Non mesenteric lymph nodes (except supraclavicular)
Allowable Values
1yes
2not reported

178DST_R_ADD_NONMES_LN_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



179DST_R_ADD_NONMES_LN_TXTstring (250)Required:false
Free test describing non-mesenteric lymph nodes (except supraclavicular) involved in additional distant recurrence

180DST_R_ADD_SUPRA_LNnumber (1,0)Required:false
Site(s) of involvement at time of additional distant recurrence Supraclavicular nodes
Allowable Values
1yes
2not reported

181DST_R_ADD_SUPRA_LN_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



182DST_R_ADD_BRAINnumber (1,0)Required:false
Site(s) of involvement at time of additional distant recurrence Brain
Allowable Values
1yes
2not reported

183DST_R_ADD_BRAIN_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



184DST_R_ADD_SKINnumber (1,0)Required:false
Site(s) of involvement at time of additional distant recurrence Skin, except incision Specify site (text):
Allowable Values
1yes
2not reported

185DST_R_ADD_SKIN_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



186DST_R_ADD_SKIN_TXTstring (250)Required:false
Free text describing site of additional distant recurrence in skin

187DST_R_ADD_ADRENALnumber (1,0)Required:false
Site(s) of involvement at time of additional distant recurrence Adrenal gland
Allowable Values
1yes
2not reported

188DST_R_ADD_ADRENAL_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



189DST_R_ADD_OTHnumber (1,0)Required:false
Site(s) of involvement at time of additional distant recurrence Other Specify site (text):
Allowable Values
1yes
2not reported

190DST_R_ADD_OTH_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



191DST_R_ADD_OTH_TXTstring (250)Required:false
Free text describing other site of additional distant recurrence

192NEW_CRC_PRIMnumber (1,0)Required:true
Did the proband have a new primary colorectal cancer diagnosis after the original CRC diagnosis (after start date to final chart date)? NOTE: Additional cancer information may exist in the individual.CANCER table
Allowable Values
1Yes
2No
8Not Asked
9Unknown


193NEW_CRC1_TUMOR_NOnumber (2,0)Required:true
Tumor number should correspond with information from the CANCER file

194NEW_CRC1_ICDstring (7)Required:false
ICD code of 1st new CRC PRIMARY If SYNCHRONOUS primaries, please record the LARGEST. (NEW_PRIMARY_1)
195NEW_CRC1_DXDATEstring (8)Required:false
DIAGNOSIS DATE OF 1st New CRC PRIMARY
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



196NEW_CRC1_SURGnumber (1,0)Required:false
Surgical treatment performed for 1st New CRC PRIMARY?
Allowable Values
1Yes
2No
8Not Asked
9Unknown


197NEW_CRC1_SURG_TYPEnumber (2,0)Required:false
Type of surgical treatment for new CRC primary (Can use SEER coding)
Allowable Values
2Local tumor destruction, i.e. laser, electrocautery
3Local surgical excision with specimen i.e. trans anal excision, polypectomy, snare
4Right Hemi colectomy
5Left Hemi colectomy
6Hemi colectomy Side not specified: not total
7Low Anterior resection
8Total Colectomy
9Total Proctectomy
10Total Proctocolectomy
11Abdominoperineal resection
12Segmental / Wedge / Partial Resection NOS
77Other (Specify):
88Not Asked
99Unknown


198NEW_CRC1_SURG_TYPE_TXTstring (250)Required:false
Free text describing other type of surgery for 1st new CRC primary
199NEW_CRC1_SURG_DATEstring (8)Required:false
Date of 1st resection for 1st new CRC primary
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



200NEW_CRC1_SURG_LOCALnumber (1,0)Required:false
Operative findings , local (residual tumor) for 1st new CRC primary (obtain information from the operative report and/or the discharge summary NOT pathology report)
Allowable Values
1Tumor not entirely resected
2Tumor entirely resected
8Not Asked
9Unknown


201NEW_CRC1_SURG_OTHORGnumber (1,0)Required:false
Were other organs (partial or total) removed at definitive surgery for 1st new CRC primary ?
Allowable Values
1Yes and site/organ specified
2Yes but site/organ not specified
3No
8Not asked
9Unknown


202NEW_CRC1_SURG_OTHORG_SM_INTESTnumber (1,0)Required:false
If small intestine (partial or total) were removed, please specify:
Allowable Values
1yes
2not reported


203NEW_CRC1_SURG_OTHORG_LIVERnumber (1,0)Required:false
If liver (partial or total) was removed, please specify:
Allowable Values
1yes
2not reported


204NEW_CRC1_SURG_OTHORG_APPENDIXnumber (1,0)Required:false
If appendix (partial or total) was removed, please specify:
Allowable Values
1yes
2not reported


205NEW_CRC1_SURG_OTHORG_OVARY_NOSnumber (1,0)Required:false
If ovary (partial or total) were removed and no information on which side (left or right) , please specify:
Allowable Values
1yes
2not reported


206NEW_CRC1_SURG_OTHORG_OVARY_Rnumber (1,0)Required:false
If right ovary (partial or total) was removed, please specify:
Allowable Values
1yes
2not reported


207NEW_CRC1_SURG_OTHORG_OVARY_Lnumber (1,0)Required:false
If left ovary (partial or total) was removed, please specify:
Allowable Values
1yes
2not reported


208NEW_CRC1_SURG_OTHORG_OVARY_Bnumber (1,0)Required:false
If both ovaries (partial or total) were removed, please specify:
Allowable Values
1yes
2not reported


209NEW_CRC1_SURG_OTHORG_SPLEENnumber (1,0)Required:false
If spleen (partial or total) was removed, please specify:
Allowable Values
1yes
2not reported


210NEW_CRC1_SURG_OTHORG_BLADDERnumber (1,0)Required:false
If bladder (partial or total) was removed, please specify:
Allowable Values
1yes
2not reported


211NEW_CRC1_SURG_OTHORG_OTHnumber (1,0)Required:false
If other organs (partial or total) were removed, please specify:
Allowable Values
1yes
2not reported


212NEW_CRC1_SURG_OTHORG_OTH_TXTstring (250)Required:false
Free text describing other organs (partial or total) removed COMMA SEPERATED IF MORE THAN ONE

213NEW_CRC1_SURG_MARGINnumber (1,0)Required:false
Did the 1st new CRC primary reach surgical resection margins? (Source: Pathology report)
Allowable Values
1Positive, proximal (Tumor is seen at proximal surgical resection margin)
2Positive, distal (Tumor is seen at distal surgical resection margin)
3Positive, radial (Tumor is seen at radial surgical resection margin)
4Positive, more than one margins defined.
5Positive, NOS (Tumor is seen at surgical resection margin, margin not defined)
6Negative (all surgical resection margins are free of tumor)
8Not Asked
9Unknown


214NEW_CRC1_METnumber (1,0)Required:false
Was distant metastatic disease found at surgery for 1st new CRC primary?
Allowable Values
1Yes and site/organ specified
2Yes but site/organ not specified
3No
8Not asked
9Unknown


215NEW_CRC1_MET_ASCITESnumber (1,0)Required:false
Site of Metastatic Disease: Ascites
Allowable Values
1yes
2not reported


216NEW_CRC1_MET_MESEN_LNnumber (1,0)Required:false
Site of Metastatic Disease: Mesenteric lymph nodes, other than in mesentery of planned resection
Allowable Values
1yes
2not reported


217NEW_CRC1_MET_LIVERnumber (1,0)Required:false
Site of Metastatic Disease: Liver
Allowable Values
1yes
2not reported


218NEW_CRC1_MET_LUNGnumber (1,0)Required:false
Site of Metastatic Disease: Lung
Allowable Values
1yes
2not reported


219NEW_CRC1_MET_OMENTUMnumber (1,0)Required:false
Site of Metastatic Disease: Omentum
Allowable Values
1yes
2not reported


220NEW_CRC1_MET_ABD_WALLnumber (1,0)Required:false
Site of Metastatic Disease: Abdominal wall
Allowable Values
1yes
2not reported


221NEW_CRC1_MET_OVARYnumber (1,0)Required:false
Site of Metastatic Disease: Ovary(s)
Allowable Values
1yes
2not reported


222NEW_CRC1_MET_BONEnumber (1,0)Required:false
Site of Metastatic Disease: Bone
Allowable Values
1yes
2not reported


223NEW_CRC1_MET_PERITOnumber (1,0)Required:false
Site of Metastatic Disease: Peritoneum
Allowable Values
1yes
2not reported


224NEW_CRC1_MET_MESENnumber (1,0)Required:false
Site of Metastatic Disease: Mesentery
Allowable Values
1yes
2not reported


225NEW_CRC1_MET_OTHnumber (1,0)Required:false
Site of Metastatic Disease: Other
Allowable Values
1yes
2not reported


226NEW_CRC1_MET_OTH_TXTstring (250)Required:false
Free text describing other site of Metastatic Disease COMMA SEPERATED IF MORE THAN ONE

227NEW_CRC1_MET_RESECTnumber (1,0)Required:false
Was this metastasis resected immediately (within 3 months) after baseline surgery) (if applicable)
Allowable Values
1All metastases entirely resected
2At least one metastasis not entirely resected
3Not resected (No surgery)
8Not Asked
9Unknown

228NEW_CRC1_MET_RESECT_DATEstring (8)Required:false
Date metastasis was resected (only if metastasis was completely or incompletely resected):
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



229NEW_CRC1_Tnumber (1,0)Required:false
Clinicopathologic summary stage of disease. Tumor Stage of 1st new CRC primary (0-4)
Allowable Values
0Carcinoma in situ/TIS
1Tumor invades submucosa
2Tumor invades muscularis propria
3Tumor invades through muscularis propria into submucosa or into non peritonealized pericolic or perirectal tissues
4Tumor directly invades other organs/structures/perforates visceral peritonium
8Not Asked
9Unknown


230NEW_CRC1_Nnumber (1,0)Required:false
Nodal stage of 1st new CRC primary (0-3)
Allowable Values
0No regional lymph node metastasis
1Metastasis in 1 to 3 regional lymph nodes
2Metastasis in 4 or more regional lymph nodes
8Not Asked
9Unknown


231NEW_CRC1_Mnumber (1,0)Required:false
Metastasis stage of 1st new CRC primary (0-1)
Allowable Values
0No distant metastasis
1Distant metastasis is present
8Not Asked
9Unknown


232NEW_CRC1_T_SRCnumber (1,0)Required:false
Source of information for tumor stage:
Allowable Values
1Pathology Report
2Clinic Note/Discharge Summary
3Other Specify (text):
8Not Asked
9Unknown


233NEW_CRC1_T_SRC_TXTstring (250)Required:false
Source of information for tumor stage: OTHER

234NEW_CRC1_N_SRCnumber (1,0)Required:false
Source of information for nodal stage:
Allowable Values
1Pathology Report
2Clinic Note/Discharge Summary
3Other Specify (text):
8Not Asked
9Unknown


235NEW_CRC1_N_SRC_TXTstring (250)Required:false
Source of information for nodal stage: OTHER

236NEW_CRC1_M_SRCnumber (1,0)Required:false
Source of information for metastasis stage):
Allowable Values
1Pathology Report
2Clinic Note/Discharge Summary
3Operative Note
4Radiology report (US, CT, MRI etc.)
5Other Specify (text):
8Not Asked
9Unknown


237NEW_CRC1_M_SRC_TXTstring (250)Required:false
Source of information for metastasis stage: OTHER

238NEW_CRC1_CHEMOnumber (1,0)Required:false
Was chemotherapy given for treatment of the new primary colorectal cancer(s)?
Allowable Values
1Yes
2No
8Not Asked
9Unknown


239NEW_CRC1_CHEMO_METHODnumber (1,0)Required:false
What method of chemotherapy was applied for treatment of the new primary colorectal cancer(s)? Note: Multiple methods and agents are possible. If so they should be recorded in order given ie Neo Adjuvant first > Adjuvant > Palliative last
Allowable Values
1Adjuvant
2Palliative
3Pseudo Adjuvant
4Neo Adjuvant (pre operative)
8Not Asked
9Unknown

240NEW_CRC1_CHEMO1_DATEstring (8)Required:false
Date of 1st chemotherapy treatment of the CRC primary(s) in the eligibility period
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



241NEW_CRC1_CHEMO1_AGTnumber (1,0)Required:false
Pseudo gateway question to capture overall “missing/unknown agent”
Allowable Values
1specified
8Not Asked
9Unknown


242NEW_CRC1_CHEMO1_AGT_5FUnumber (1,0)Required:false
5 FU / FLUOROURACIL/ ADRUCIL CHEMOTHERAPEUTIC AGENT first course only. Does not include medications given to control or suppress side effect. Also the list is abbreviated and another variable “other” added to list additional drugs
Allowable Values
1yes
2not reported


243NEW_CRC1_CHEMO1_AGT_FAnumber (1,0)Required:false
FA (FOLINIC ACID) / LEUCOVORIN / WELLCOVORIN
Allowable Values
1yes
2not reported


244NEW_CRC1_CHEMO1_AGT_CPT11number (1,0)Required:false
CPT11/ IRINOTECAN / CAMPTOSAR
Allowable Values
1yes
2not reported


245NEW_CRC1_CHEMO1_AGT_OXALnumber (1,0)Required:false
OXALIPLATIN / ELOXATIN
Allowable Values
1yes
2not reported


246NEW_CRC1_CHEMO1_AGT_LEVAnumber (1,0)Required:false
LEVAMISOLE
Allowable Values
1yes
2not reported


247NEW_CRC1_CHEMO1_AGT_XELOnumber (1,0)Required:false
XELODA / CAPECITABINE
Allowable Values
1yes
2not reported


248NEW_CRC1_CHEMO1_AGT_AVASnumber (1,0)Required:false
AVASTIN / BEVACIZUMAB
Allowable Values
1yes
2not reported


249NEW_CRC1_CHEMO1_AGT_ERBInumber (1,0)Required:false
ERBITUX/ CETUXIMAB
Allowable Values
1yes
2not reported


250NEW_CRC1_CHEMO1_AGT_GEMZnumber (1,0)Required:false
GEMZAR
Allowable Values
1yes
2not reported


251NEW_CRC1_CHEMO1_AGT_OTHnumber (1,0)Required:false
OTHER AGENT CHEMOTHERAPEUTIC AGENT
Allowable Values
1yes
2not reported


252NEW_CRC1_CHEMO1_AGT_OTH_TXTstring (250)Required:false
Free text describing OTHER CHEMOTHERAPEUTIC AGENT, COMMA SEPERATED IF MORE THAN ONE

253NEW_CRC1_RADnumber (1,0)Required:false
Was radiation given for treatment of the new primary colorectal cancer(s)?
Allowable Values
1Yes
2No
8Not Asked
9Unknown


254NEW_CRC1_RAD_METHODnumber (1,0)Required:false
What method of radiotherapy was applied for treatment of the new primary colorectal cancer(s)?
Allowable Values
1Adjuvant
2Palliative
3Pseudo Adjuvant
4Neo Adjuvant (pre operative)
8Not Asked
9Unknown

255NEW_CRC1_RAD1_DATEstring (8)Required:false
Date of 1st radiotherapy treatment of the CRC primary(s) in the eligibility period
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



256NEW_CRC1_TREAT_OTHnumber (1,0)Required:false
Were other treatment methods applied for new primary colorectal cancer(s)?
Allowable Values
1Yes (Specify)
2No
8Not Asked
9Unknown


257NEW_CRC1_TREAT_OTH_TXTstring (250)Required:false
free text describing 1st other treatment methods applied for new CRC primary (NEW_CRC1_TREAT_OTH=1,2), Comma separated list of other agents(s

258NEW_CRC1_SYNCnumber (1,0)Required:false
Were synchronous new CRC primaries diagnosed?
Allowable Values
1Yes
2No
8Not Asked
9Unknown


259NEW_CRC1_SYNC_NUMnumber (2,0)Required:false
#_____ of SYNCHRONOUS PRIMARY(S)
Allowable Values
1 to 8 or 88, 99Range
88Not asked
99unknown


260NEW_CRC1_SYNC2_TUMOR_NOnumber (2,0)Required:true
Tumor number should correspond with information from the CANCER file

261NEW_CRC1_SYNC2_ICDstring (7)Required:false
ICD code of 2nd SYNCHRONOUS new CRC PRIMARY DIAGNOSIS TYPE. (Please record the 2nd largest. (NEW_PRIMARY_2)
262NEW_CRC1_SYNC2_DXDATEstring (8)Required:false
DIAGNOSIS DATE OF 2nd SYNCHRONOUS new CRC PRIMARY
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



263NEW_CRC1_SYNC2_SURG_TYPEnumber (2,0)Required:false
Surgical treatment for 2nd synchronous new CRC (Can use SEER coding to derive)
Allowable Values
1No Surgery
2Local tumor destruction, i.e. laser, electrocautery
3Local surgical excision with specimen i.e. trans anal excision, polypectomy, snare
4Right Hemi colectomy
5Left Hemi colectomy
6Hemi colectomy Side not specified: not total
7Low Anterior resection
8Total Colectomy
9Total Proctectomy
10Total Proctocolectomy
11Abdominoperineal resection
12Segmental / Wedge / Partial Resection NOS
77Other (Specify):
88Not Asked
99Unknown


264NEW_CRC1_SYNC2_SURG_TYPE_TXTstring (250)Required:false
free text describing other surgery for 2nd synchronous new CRC

265NEW_CRC1_SYNC2_SURG_LOCALnumber (1,0)Required:false
Operative findings , local (residual tumor) (obtain information from the operative report and/or the discharge summary NOT pathology report)
Allowable Values
1Tumor not entirely resected
2Tumor entirely resected
8Not Asked
9Unknown


266NEW_CRC1_SYNC2_SURG_MARGINnumber (1,0)Required:false
Did the tumor reach surgical resection margins? (Source: Pathology report)
Allowable Values
1Positive, proximal (Tumor is seen at proximal surgical resection margin)
2Positive, distal (Tumor is seen at distal surgical resection margin)
3Positive, radial (Tumor is seen at radial surgical resection margin)
4Positive, more than one margins defined.
5Positive, NOS (Tumor is seen at surgical resection margin, margin not defined)
6Negative (all surgical resection margins are free of tumor)
8Not Asked
9Unknown


267NEW_CRC1_SYNC3_TUMOR_NOnumber (2,0)Required:true
Tumor number should correspond with information from the CANCER file

268NEW_CRC1_SYNC3_ICDstring (7)Required:false
ICD code of 3rd SYNCHRONOUS new CRC PRIMARY DIAGNOSIS TYPE. (Please record the 3rd largest. (NEW_PRIMARY_3)
269NEW_CRC1_SYNC3_DXDATEstring (8)Required:false
DIAGNOSIS DATE OF 3rd SYNCHRONOUS new CRC PRIMARY IN THE ELIGIBILITY PERIOD
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



270NEW_CRC1_SYNC3_SURG_TYPEnumber (2,0)Required:false
Surgical treatment for 3rd SYNCHRONOUS new CRC primary (Can use SEER coding to derive)
Allowable Values
1No Surgery
2Local tumor destruction, i.e. laser, electrocautery
3Local surgical excision with specimen i.e. trans anal excision, polypectomy, snare
4Right Hemi colectomy
5Left Hemi colectomy
6Hemi colectomy Side not specified: not total
7Low Anterior resection
8Total Colectomy
9Total Proctectomy
10Total Proctocolectomy
11Abdominoperineal resection
12Segmental / Wedge / Partial Resection NOS
77Other (Specify):
88Not Asked
99Unknown


271NEW_CRC1_SYNC3_SURG_TYPE_TXTstring (250)Required:false
Free text describing other surgery for 3rd synchronous new CRC

272NEW_CRC1_SYNC3_SURG_LOCALnumber (1,0)Required:false
Operative findings , local (residual tumor) or 3rd synchronous new CRC (obtain information from the operative report and/or the discharge summary NOT pathology report)
Allowable Values
1Tumor not entirely resected
2Tumor entirely resected
8Not Asked
9Unknown


273NEW_CRC1_SYNC3_SURG_MARGINnumber (1,0)Required:false
Did the or 3rd synchronous new CRC reach surgical resection margins? (Source: Pathology report)
Allowable Values
1Positive, proximal (Tumor is seen at proximal surgical resection margin)
2Positive, distal (Tumor is seen at distal surgical resection margin)
3Positive, radial (Tumor is seen at radial surgical resection margin)
4Positive, more than one margins defined.
5Positive, NOS (Tumor is seen at surgical resection margin, margin not defined)
6Negative (all surgical resection margins are free of tumor)
8Not Asked
9Unknown


274NEW_CRC2_PRIMnumber (1,0)Required:false
Was second “non Synchronous” CRC diagnosed within the follow-up period after the diagnosis of first new CRC? NOTE: Additional cancer information may exist in the individual.CANCER table
Allowable Values
1Yes
2No
8Not Asked
9Unknown


275NEW_CRC2_TUMOR_NOnumber (2,0)Required:true
Tumor number should correspond with information from the CANCER file

276NEW_CRC2_ICDstring (7)Required:false
second “non synchronous” CRC diagnosed within the follow-up period (within 4 yrs of incidence CRC)
277NEW_CRC2_DXDATEstring (8)Required:false
Diagnosis Date 2nd new “non-synchronous” CRC primary(s) in the follow-up period
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



278NEW_CRC2_SURG_TYPEnumber (2,0)Required:false
Surgical treatment for 2nd non-synchronous CRC (Can use SEER coding to derive)
Allowable Values
1No Surgery
2Local tumor destruction, i.e. laser, electrocautery
3Local surgical excision with specimen i.e. trans anal excision, polypectomy, snare
4Right Hemi colectomy
5Left Hemi colectomy
6Hemi colectomy Side not specified: not total
7Low Anterior resection
8Total Colectomy
9Total Proctectomy
10Total Proctocolectomy
11Abdominoperineal resection
12Segmental / Wedge / Partial Resection NOS
77Other (Specify):
88Not Asked
99Unknown


279NEW_CRC2_SURG_TYPE_TXTstring (250)Required:false
Free text describing other surgical treatment for 2nd non-synchronous CRC

280NEW_CRC2_SURG_TYPE_LOCALnumber (1,0)Required:false
Operative findings , local (residual tumor) 2nd non-synchronous CRC (obtain information from the operative report and/or the discharge summary NOT pathology report)
Allowable Values
1Tumor not entirely resected
2Tumor entirely resected
8Not Asked
9Unknown


281NEW_CRC2_SURG_TYPE_MARGINnumber (1,0)Required:false
Did the 2nd non-synchronous CRC reach surgical resection margins? (Source: Pathology report)
Allowable Values
1Positive, proximal (Tumor is seen at proximal surgical resection margin)
2Positive, distal (Tumor is seen at distal surgical resection margin)
3Positive, radial (Tumor is seen at radial surgical resection margin)
4Positive, more than one margins defined.
5Positive, NOS (Tumor is seen at surgical resection margin, margin not defined)
6Negative (all surgical resection margins are free of tumor)
8Not Asked
9Unknown


282NEW_CRC2_SYNCnumber (1,0)Required:false
Were 2nd synchronous new CRC primaries diagnosed?
Allowable Values
1Yes
2No
8Not Asked
9Unknown


283NEW_CRC2_SYNC_NUMnumber (2,0)Required:false
#_____ of 2nd SYNCHRONOUS PRIMARY(S)
Allowable Values
1 to 8 or 88, 99Range
88Not asked
99unknown


284NEW_NONCRC_PRIMnumber (1,0)Required:false
Did the proband have a new non-CRC primary diagnosis after the original CRC diagnosis (after incident CRC date to date of final chart note) NOTE: Additional cancer information may exist in the individual.CANCER table
Allowable Values
1Yes
2No
8Not Asked
9Unknown


285NEW_NONCRC1_ICDstring (7)Required:false
ICD code for 1st new non-CRC PRIMARY

286NEW_NONCRC2_ICDstring (7)Required:false
ICD code for 2nd new non-CRC PRIMARY

287NEW_NONCRC3_ICDstring (7)Required:false
ICD code for 3rd new non-CRC PRIMARY

288LAST_STATUSnumber (1,0)Required:true
final vital status with cause of death (COD)
Allowable Values
1alive and cancer free
2alive with cancer
3alive cancer status unknown
4deceased due to Cancer
5deceased not due to cancer
6deceased cancer status unknown
7deceased cause unknown
8Not Asked
9Unknown

289DEATH_DATEstring (8)Required:false
DATE OF DEATH
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



290DEATH_CAUSEstring (25)Required:false
What was the patient??s cause of death? Cause of Death: (if known use ICD code)
291LAST_CHART_DATEstring (8)Required:false
Date of Last (Most Recent) Physician Chart Note found by the Abstractor (Operative Notes, Discharge Summary, Clinic Notes, Chemotherapy and/or Radiotherapy Notes)
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year


292COMPLETE_DATEstring (8)Required:false
Date Form Completed (date review/abstraction completed)
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



293LR_DST_RECURnumber (1,0)Required:false
Did the patient have at least one locoregional or distal recurrence after CRC diagnosis? (Ideally interval between diagnosis date and final chart review date should be at least 4 years)
Allowable Values
1Yes and site/organ specified
2Yes but site/organ not specified
3No
8Not asked
9Unknown


294LR_DST1_ANASTnumber (1,0)Required:false
Site(s) of involvement at time of first locoregional or distal recurrence (please circle all that apply): Anastomosis:
Allowable Values
1yes
2Not reported

295LR_DST1_ANAST_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



296LR_DST1_MESENnumber (1,0)Required:false
Site(s) of involvement at time of first locoregional recurrence (please circle all that apply): Mesentery
Allowable Values
1yes
2Not reported

297LR_DST1_MESEN_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



298LR_DST1_ABD_WALLnumber (1,0)Required:false
Site(s) of involvement at time of first locoregional recurrence (please circle all that apply): Abdominal Wall (not incisional)
Allowable Values
1yes
2Not reported

299LR_DST1_ABD_WALL_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



300LR_DST1_INCSnumber (1,0)Required:false
Site(s) of involvement at time of first locoregional recurrence (please circle all that apply): Incisional
Allowable Values
1yes
2Not reported

301LR_DST1_INCS_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



302LR_DST1_PELVISnumber (1,0)Required:false
Site(s) of involvement at time of first distal or locoregional recurrence (please circle all that apply): Pelvis
Allowable Values
1yes
2Not reported

303LR_DST1_PELVIS_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



304LR_DST1_LIVERnumber (1,0)Required:false
Site(s) of involvement at time of first distant or locoregional recurrence Liver
Allowable Values
1yes
2Not reported

305LR_DST1_LIVER_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



306LR_DST1_LUNGnumber (1,0)Required:false
Site(s) of involvement at time of first distant or locoregional recurrence Lung
Allowable Values
1yes
2Not reported

307LR_DST1_LUNG_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



308LR_DST1_BONEnumber (1,0)Required:false
Site(s) of involvement at time of first distant or locoregional recurrence Bone
Allowable Values
1yes
2Not reported

309LR_DST1_BONE_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



310LR_DST1_ASCITESnumber (1,0)Required:false
Site(s) of involvement at time of first distant or locoregional recurrence Ascites
Allowable Values
1yes
2Not reported

311LR_DST1_ASCITES_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



312LR_DST1_NONMES_LNnumber (1,0)Required:false
Site(s) of involvement at time of first distant or locoregional recurrence Non-mesenteric lymph nodes (except supraclavicular)
Allowable Values
1yes
2Not reported

313LR_DST1_NONMES_LN_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



314LR_DST1_NONMES_LN_TXTstring (250)Required:false
Free text describing specific non-mesenteric lymph nodes (except supraclavicular)

315LR_DST1_SUPRA_LNnumber (1,0)Required:false
Site(s) of involvement at time of first distant or locoregional recurrence Supraclavicular nodes
Allowable Values
1yes
2Not reported

316LR_DST1_SUPRA_LN_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



317LR_DST1_BRAINnumber (1,0)Required:false
Site(s) of involvement at time of first distant or locoregional recurrence Brain
Allowable Values
1yes
2Not reported

318LR_DST1_BRAIN_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



319LR_DST1_SKINnumber (1,0)Required:false
Site(s) of involvement at time of first distant or locoregional recurrence: Skin, except incision Specify site (text):
Allowable Values
1yes
2Not reported

320LR_DST1_SKIN_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



321LR_DST1_SKIN_TXTstring (250)Required:false
Free text describing first distant or locoregional recurrence in skin, except incision

322LR_DST1_ADRENALnumber (1,0)Required:false
Site(s) of involvement at time of first distant or locoregional recurrence: Adrenal gland
Allowable Values
1yes
2Not reported

323LR_DST1_ADRENAL_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year



324LR_DST1_OTHnumber (1,0)Required:false
Site(s) of involvement at time of first distant or locoregional recurrence Other Specify site (text):
Allowable Values
1Yes
2Not reported


325LR_DST1_OTH_TXTstring (250)Required:false
Free text describing other site of first distant or locoregional recurrence
326LR_DST1_OTH_DATEstring (8)Required:false
First Diagnosed Month First Diagnosed Day (optional) First Diagnosed Year
Date Value Check
The date must follow to the following format:

Format YYYYMMDD. Must consist of valid date.
Components of date should be right justified and zero filled.
MM = 01 – 12, 88, 99
DD = 01 – 31, 88, 99
YYYY = Minimum year – system date year, 8888, 9999
Use 88, 8888 for not currently known, in progress to obtain information.
Use 99, 9999 for not known.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If MM = 99 then DD must = 99.
If century is known, but year is unknown then give an estimate of year or code YYYY = 9999.
If YYYY = 9999 then MM and DD must = 99.

The following special parameters are used:
1900Minimum year