Summary tables - January 2020

TABLE 1. FAMILY RECRUITMENTa
 
  Male Female Total
       
Population-based Families*     13188
Case probandsb 4320 4420 8740
Affected relativesb 340 383 723
Unaffected relativesc 7403 9952 17355
Spouse Controlsd 363 561 924
Control probandsc 2071   2205  4276
Relatives of controls (Australia only) 310 467 777
 Total population-based individuals 14807  17988  32795 
       
Clinic-based Families**     1860
Affected probandsb 707 648 1355
Unaffected probandsc 131 300 431
Affected relativesb 445 463 909
Unaffected relativesc 3079 3937 7016
Total clinic-based individuals 4362 5348 9711
       
Total Individuals 19169 23336 42506
Total Families     15049
* Includes population-based case proband families from all sites and population-based control proband families from Australia site.
** Includes all clinic-based proband families (counts family ID of affected and unaffected clinic-based probands).
a. Baseline epi data (excluding proxy completion) for females and males
b. Affected with colorectal cancer at baseline interview or biospecimen collection
c. No history of colorectal cancer at baseline interview or biospecimen collection
d. Non blood relation and spouse of case proband recruited to serve as a control.
Note: Blood and non-blood relatives/individuals excluding the probands.

 

TABLE 2. FAMILY DATAa
    Male Female Total
A.Population Based Case Colon Cancer Families      
Probandsb Baseline epi dataa 4319 4420 8739
  1st Follow-up epi data 2640 2971 5611
  2nd Follow-up epi data 1814 2094 3908
  3rd Follow-up epi data 1022 1251 2273
  4th Follow-up epi data 363 433  796 
  FFQ datae 2093 2407 4500
  Blood/buccal samples 3493 3637 7130 
  Polyp material 17 9 26
  Tumor material 3573 3447 7020
  (CRC tumor material)i 3531 3386 6917
  (Other tumor material)j 103 149 252
  Clinical Dx and Treatment Info 2028 1997 4025
 Relativesc Baseline epi dataa 7743 10334 18077
  1st Follow-up epi data 6004 8277 14281
  2nd Follow-up epi data 4546 6425 10971
  3rd Follow-up epi data 2806 3965 6771
  4th Follow-up epi data 441 677 1118
  FFQ datae 3279 4616 7895
  Blood/buccal samples 4371 6131 10502
  Polyp material 9 12 21
  Tumor material 305 380 685
  (CRC tumor material)i 238 255 493
  (Other tumor material)j 80 148 228
  Clinical Dx and Treatment info 50 52 102
Spouse Controlsf Baseline epi dataa 363 560 923
  1st Follow-up epi data 295 482 777
  2nd Follow-up epi data 229 387 616
  3rd Follow-up epi data 167 286 453
  4th Follow-up epi data 41 63 104
  FFQ datae 211 318 529
  Blood/buccal samples 259 408 667
  Polyp material 0 0 0
  Tumor material 4 10 14
  (CRC tumor material)i 1 3 4
  (Other tumor material)j 3 7 10
   Clinical Dx and Treatment info  0  0  0
B.Population Based Control Colon Cancer Families      
Probandsd Baseline epi dataa 2071 2205 4276
  1st Follow-up epi data 668 592 1260
  2nd Follow-up epi data 335 279 614
  3rd Follow-up epi data 0 0 0
  4th Follow-up epi data 0 0 0
  FFQ datae 1151 1025 2176
   Blood/buccal samples 1364  1424  2788 
  Polyp material      
  Tumor material 0 0 0
  (CRC tumor material)i 0 0 0
  (Other tumor material)j 0 0 0
  Clinical Dx and Treatment Info 0 0 0
 Relativesg Baseline epi dataa 310 467 777
  1st Follow-up epi data 0 0 0
  2nd Follow-up epi data 0 0 0
  3rd Follow-up epi data 0 0 0
  4th Follow-up epi data 0 0 0
  FFQ datae 259 382 641
  Blood/buccal samples 5 5 10
  Polyp material 0 0 0
  Tumor material 0 0 0
  (CRC tumor material)i 0 0 0
  (Other tumor material)j 0 0 0
  Clinical Dx and Treatment info 0 0 0
         
C.Clinic Based Colon Cancer Families*      
Affected Probandsb Baseline epi dataa 707 648 1355
  1st Follow-up epi data 508 499 1007
  2nd Follow-up epi data 362 374 736
  3rd Follow-up epi data 185 189 374
  4th Follow-up epi data 44 49 93
  FFQ datae 236 252 488
  Blood/buccal samples 636 600 1236
  Polyp material 21 23 44
  Tumor material 577 532 1109
  (CRC tumor material)i 567 516 1083
  (Other tumor material)j 81 96 177
  Clinical Dx and Treatment info 355 292 647
 Unaffected Probandsd Baseline epi dataa 130 300 430
  1st Follow-up epi data 122 277 399
  2nd Follow-up epi data 97 219 316
  3rd Follow-up epi data 44 92 136
  4th Follow-up epi data 4 10 14
  FFQ datae 72 183 255
  Blood/buccal samples 117 278 395
  Polyp material 18 34 52
  Tumor material 30 86 116
  (CRC tumor material)i 1 9 10
  (Other tumor material)j 29 82 111
  Clinical Dx and Treatment info 2 2 4
Relativesh Baseline epi dataa 3523 4400 7924
  1st Follow-up epi data 3000 3800 6801
  2nd Follow-up epi data 2265 2948 5213
  3rd Follow-up epi data 1095 1532 2627
  4th Follow-up epi data 116 154 270
  FFQ datae 1922 2564 4486
  Blood/buccal samples 3036 3905 6942
  Polyp material 123 133 256
  Tumor material 479 591 1070
  (CRC tumor material)i 331 360 691
  (Other tumor material)j 172 277 449
  Clinical Dx and Treatment info 15 7 22

 

a. Baseline epi data (excluding proxy completion) for females and males

b. Affected with colorectal cancer at baseline interview or biospecimen collection

c. Affected and unaffected, blood and non-blood, relatives of population based case probands, at baseline interview.

d. No history of colon cancer at baseline interview.

e. Food Frequency Questionnaire

f. Non blood relation and spouse of case proband recruited to serve as a control.

g. Affected and unaffected, blood and non-blood, relatives of population based control probands, at baseline interview.

h. Affected and unaffected, blood and non-blood, relatives of clinic based probands, at baseline interview or biospecimen collection.

i. Individuals diagnosed with colorectal cancer and at least one colorectal tumor specimen obtained.

j. Individuals diagnosed with non-colorectal cancer and at least one tumor specimen obtained. 

* Includes all clinic-based probands and their blood or non-blood relatives
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